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Adjuvant molecules / TLR4-IN-C34-C2-COOH
TLR4-IN-C34-C2-COOH chemical structure
CAT. NO. DC47884Featured

TLR4-IN-C34-C2-COOH

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Ships from ShanghaiFor research use only
Product overview

Description & Application

TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.

CAS No.1159408-54-4
Chemical NameTLR4-IN-C34-C2-COOH
Synonyms5-{[(2R,3R,4R,5R,6R)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]oxy}pentanoicacid;5-[(2R,3R,4S,5R,6R)-3-Acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxypentanoic acid;5-{[(2R,3R,4R,5R,6R)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]oxy}pentanoic acid;5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid;TLR4-IN-C34-C2-COOH
SMILESO1[C@H]([C@@H]([C@@H]([C@H]([C@H]1COC(C)=O)OC(C)=O)OC(C)=O)NC(C)=O)OCCCCC(=O)O
FormulaC19H29NO11
M.Wt447.433666944504
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationAdjuvant Molecules
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
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C₁V₁ = C₂V₂
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Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg22.3497 mL4.4699 mL2.2350 mL
25 mg55.8742 mL11.1748 mL5.5874 mL
50 mg111.7484 mL22.3497 mL11.1748 mL
100 mg223.4968 mL44.6994 mL22.3497 mL
250 mg558.7420 mL111.7484 mL55.8742 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.