Gardiquimod, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod specifically activates TLR7 when used at concentrations below 10 μM12.
| CAS No. | 1020412-43-4 |
| Chemical Name | 1-[4-Amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol |
| Synonyms | Gardiquimod; |
| SMILES | CC(O)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N |
| Formula | C17H23N5O |
| M.Wt | 313.4 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 31.9081 mL | 6.3816 mL | 3.1908 mL |
| 25 mg | 79.7703 mL | 15.9541 mL | 7.9770 mL |
| 50 mg | 159.5405 mL | 31.9081 mL | 15.9541 mL |
| 100 mg | 319.0810 mL | 63.8162 mL | 31.9081 mL |
| 250 mg | 797.7026 mL | 159.5405 mL | 79.7703 mL |
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