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Adjuvant molecules / TLR4-IN-C34
TLR4-IN-C34 chemical structure
CAT. NO. DC31025Featured

TLR4-IN-C34

Pack size & price

USD
TotalUS$700
Ships from ShanghaiFor research use only
Product overview

Description & Application

TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis[1][2].

CAS No.40592-88-9
Chemical NameTLR4-IN-C34
SynonymsC34,C-34,C 34;Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate;2-Acetamidopyranoside;Isopropyl 2-(acetylamino)-2-deoxy α-D-glucopyranoside 3,4,6-triacetate
SMILESO=C(C)N[C@H]1[C@@H](OC(C)C)O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C
FormulaC17H27NO9
M.Wt389.397
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
Publication1. Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013 Jun 12;8(6):e65779. 2. Wipf P, et al. Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4). Tetrahedron Lett. 2015 Jun 3;56(23):3097-3100.
Product classificationAdjuvant Molecules
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
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C₁V₁ = C₂V₂
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Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg25.6807 mL5.1361 mL2.5681 mL
25 mg64.2018 mL12.8404 mL6.4202 mL
50 mg128.4037 mL25.6807 mL12.8404 mL
100 mg256.8073 mL51.3615 mL25.6807 mL
250 mg642.0183 mL128.4037 mL64.2018 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.