KRN-7000(S34)
DC67239
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1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity12.
| CAS No. | 1062444-54-5 |
| Chemical Name | 1V209(TLR7 agonist T7) |
| Synonyms | TLR7 agonist T7 |
| SMILES | O=C(C1C=CC(CN2C3C(=C(N=C(N=3)OCCOC)N)NC2=O)=CC=1)O |
| Formula | C16H17N5O5 |
| M.Wt | 359.33 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | 1. Battistella C, et al. Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme-Directed Assembly. Adv Healthc Mater. 2019 Dec;8(23):e1901105. 2. Shinchi H, et al. Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides. Bioconjug Chem. 2015 Aug 19;26(8):1713-23. |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 27.8296 mL | 5.5659 mL | 2.7830 mL |
| 25 mg | 69.5739 mL | 13.9148 mL | 6.9574 mL |
| 50 mg | 139.1479 mL | 27.8296 mL | 13.9148 mL |
| 100 mg | 278.2957 mL | 55.6591 mL | 27.8296 mL |
| 250 mg | 695.7393 mL | 139.1479 mL | 69.5739 mL |
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