KRN-7000(S34)
DC67239
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Loxoribine (7-Allyl-8-oxoguanosine) is a guanosine analog with anti-viral and anti-tumor activities. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist123.
| CAS No. | 121288-39-9 |
| Chemical Name | Loxoribine |
| Synonyms | Guanosine,7,8-dihydro-8-oxo-7-(2-propen-1-yl)-;7-Allyl-7 8-Dihydro-8-Oxoguanosine 95;7-ALLYL-7,8-DIHYDRO-8-OXOGUANOSINE;7-Allyl-7,8-dihydro-8-oxoguanosine (Loxoribine);7-Allyl-7,8-dihydro-8-oxoguanosine (Loxoribine);7-allyl-8-oxoguanosine;RWJ 21757;7-allyl-8-oxo-G;Loxoribine;7,8-Dihydro-8-oxo-7-allyl-guanosine;7,8-Dihydro-8-oxo-7-(2-propenyl)guanosine;Guanosine, 7,8-dihydro-8-oxo-7-(2-propenyl)-;7-Allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1H-purine-6,8-dione;7-Allyl-7,8-dihydro-8-oxoguanosine 95%;7-ALLYL-7 8-DIHYDRO-8-OXOGUANOSINE 95;7-Allyl-8-oxoguanosine |
| SMILES | C=CCN1C2=C(N(C1=O)[C@H]3[C@H](O)[C@H](O)[C@H](O3)CO)NC(NC2=O)=N |
| Formula | C13H17N5O6 |
| M.Wt | 339.30398 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Adjuvant Molecules |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 29.4721 mL | 5.8944 mL | 2.9472 mL |
| 25 mg | 73.6802 mL | 14.7360 mL | 7.3680 mL |
| 50 mg | 147.3605 mL | 29.4721 mL | 14.7360 mL |
| 100 mg | 294.7210 mL | 58.9442 mL | 29.4721 mL |
| 250 mg | 736.8024 mL | 147.3605 mL | 73.6802 mL |
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