For research use only. We do not sell to patients.
Adjuvant molecules / 3M-011
3M-011 chemical structure
CAT. NO. DC22934Featured

3M-011

Pack size & price

USD
TotalUS$550
Ships from ShanghaiFor research use only
Product overview

Description & Application

3M-011 is a potent TLR7/8 agonist and cytokine inducer; stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells; induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice.

CAS No.642473-62-9
Chemical NameN-(1-(4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-yl)methanesulfonamide
Synonyms3M011;3M 854A
SMILESCS(=O)(NC(C)(C)CN1C(COCC)=NC2=C1C3=CC=CC=C3N=C2N)=O
FormulaC18H25N5O3S
M.Wt391.49
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
Publication1. Martinson JA, et al. Cell Immunol. 2007 Nov-Dec;250(1-2):75-84. 2. Hammerbeck DM, et al. Antiviral Res. 2007 Jan;73(1):1-11.
Product classificationAdjuvant Molecules
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg25.5434 mL5.1087 mL2.5543 mL
25 mg63.8586 mL12.7717 mL6.3859 mL
50 mg127.7172 mL25.5434 mL12.7717 mL
100 mg255.4344 mL51.0869 mL25.5434 mL
250 mg638.5859 mL127.7172 mL63.8586 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.