For research use only. We do not sell to patients.
Adjuvant molecules / SMU127
SMU127 chemical structure
CAT. NO. DC12437Featured

SMU127

Pack size & price

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Ships from ShanghaiFor research use only
Product overview

Description & Application

SMU127 (SMU-127, ZINC666243) is a specific TLR1-TLR2 small molecule agonist with EC50 of 0.55 uM; stimulates NF-κB activation and promotes TNFα secretion in human macrophages and mononuclear cells, inhibits the growth of breast cancer tumors in BABL/c mice.

CAS No.903864-87-9
Chemical Nameethyl 2-(4-methylpiperazine-1-carboxamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
SynonymsSMU-127;ZINC666243
SMILESC12CCCC=1C(C(OCC)=O)=C(NC(N1CCN(C)CC1)=O)S2
FormulaC16H23N3O3S
M.Wt337.438
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationAdjuvant Molecules
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg29.6351 mL5.9270 mL2.9635 mL
25 mg74.0877 mL14.8175 mL7.4088 mL
50 mg148.1754 mL29.6351 mL14.8175 mL
100 mg296.3507 mL59.2701 mL29.6351 mL
250 mg740.8768 mL148.1754 mL74.0877 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.