BP-200-C12
DC68235
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MP2 is a methylprednisolone-derived ionizable lipid with a steroidal headgroup and three acetal-containing C8 tails. In the cited study, MP2 was formulated with DOPE, cholesterol and DMG-PEG2k for rectal mRNA delivery to inflamed colonic tissue. The MP2 formulation produced about 15-fold higher colonic luciferase signal than the study's SM102 formulation in TNBS colitis mice.
| CAS No. | Not available |
| Chemical Name | MP2 |
| Synonyms | MP 2,MP-2 |
| SMILES | CCCCCCCCOCOCCCCN(CCCCCCOC(=O)CCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C)CCCN(CCCCOCOCCCCCCCC)CCCCOCOCCCCCCCC |
| Formula | C74H132N2O14 |
| M.Wt | 1273.87 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Cationic/Ionizable Lipids |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 7.8501 mL | 1.5700 mL | 0.7850 mL |
| 25 mg | 19.6252 mL | 3.9250 mL | 1.9625 mL |
| 50 mg | 39.2505 mL | 7.8501 mL | 3.9250 mL |
| 100 mg | 78.5009 mL | 15.7002 mL | 7.8501 mL |
| 250 mg | 196.2524 mL | 39.2505 mL | 19.6252 mL |
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