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Cationic and ionizable lipids / Lipid 6
Lipid 6 chemical structure
CAT. NO. DC68234Featured

Lipid 6

Pack size & price

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Ships from ShanghaiFor research use only
Product overview

Description & Application

Lipid 6 is the lead ionizable lipid among eight candidates screened by Gao et al. for mRNA delivery to primary human immune cells. Lipid 6 LNPs were used to generate MUC1-CAR T cells ex vivo and to assess their cytotoxicity against MUC1-positive cancer cell lines in vitro. Mouse reporter-mRNA expression was studied separately; in vivo antitumor efficacy of the CAR T cells was not established.

CAS No.Not available
Chemical NameLipid 6
SynonymsLipid 6; amine-core-6 lipidoid
SMILESN(CC(O)CCCCCCCCCCCC)(CC(O)CCCCCCCCCCCC)CCOCCN(CCOCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CCN1CCN(CCOCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CC1
FormulaC102H210N6O9
M.Wt1664.84
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationCationic/Ionizable Lipids
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg6.0066 mL1.2013 mL0.6007 mL
25 mg15.0165 mL3.0033 mL1.5016 mL
50 mg30.0329 mL6.0066 mL3.0033 mL
100 mg60.0658 mL12.0132 mL6.0066 mL
250 mg150.1646 mL30.0329 mL15.0165 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.