For research use only. We do not sell to patients.
siRNA, ASO & aptamer drugs / Inotersen
Inotersen chemical structure
CAT. NO. DC67024Featured

Inotersen

Pack size & price

USD
TotalUS$1,200
Ships from ShanghaiFor research use only
Product overview

Description & Application

Inotersen is an antisense oligonucleotide that inhibits hepatic production of transthyretin (TTR). The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Inotersen sodium) that retains the same biological activity.

CAS No.1492984-65-2
Chemical NameInotersen
Synonyms0IEO0F56LV;1492984-65-2;Inotersen [USAN];ISIS 420915;Tegsedi;UNII-0IEO0F56LV;Inotersen
SMILESS=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(NC(C(C)=C2)=O)=O)O1)OCCOC)OP(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3C(NC(N)=NC2=3)=O)O1)OCCOC)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C=NC3C(NC(N)=NC2=3)=O)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C(NC(C(C)=C2)=O)=O)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C(NC(C(C)=C2)=O)=O)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C=NC3C(N)=NC=NC2=3)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C(N=C(C(C)=C2)N)=O)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C=NC3C(N)=NC=NC2=3)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C(NC(C(C)=C2)=O)=O)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C=NC3C(NC(N)=NC2=3)=O)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C=NC3C(N)=NC=NC2=3)O1)OP(O)(OC[C@@H]1[C@H](C[C@H](N2C=NC3C(N)=NC=NC2=3)O1)OP(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3C(N)=NC=NC2=3)O1)OCCOC)OP(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(NC(C(C)=C2)=O)=O)O1)OCCOC)OP(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C(C)=C2)N)=O)O1)OCCOC)OP(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C(C)=C2)N)=O)O1)OCCOC)OP(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C(N=C(C(C)=C2)N)=O)O1)OCCOC)O)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)=S)O[C@@H]1[C@@H](COP(=O)(O[C@@H]2[C@@H](COP(O)(O[C@@H]3[C@@H](CO)O[C@H]([C@@H]3OCCOC)N3C(NC(C(C)=C3)=O)=O)=S)O[C@H]([C@@H]2OCCOC)N2C(N=C(C(C)=C2)N)=O)S)O[C@H]([C@@H]1OCCOC)N1C(NC(C(C)=C1)=O)=O
FormulaC230H318N69O121P19S19
M.Wt7183.11210107803
Purity>95%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationsiRNA/ASOs/Aptamer drugs
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg1.3922 mL0.2784 mL0.1392 mL
25 mg3.4804 mL0.6961 mL0.3480 mL
50 mg6.9608 mL1.3922 mL0.6961 mL
100 mg13.9215 mL2.7843 mL1.3922 mL
250 mg34.8039 mL6.9608 mL3.4804 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.