For research use only. We do not sell to patients.
siRNA, ASO & aptamer drugs / Inclisiran
Inclisiran chemical structure
CAT. NO. DC47292Featured

Inclisiran

Pack size & price

USD
TotalUS$1,000
Ships from ShanghaiFor research use only
Product overview

Description & Application

Inclisiran (ALN-PCSsc) is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran can be used for hyperlipidemia and cardiovascular disease (CVD) research.

CAS No.1639324-58-5
Chemical NameInclisiran
SynonymsCQQ59545BV;Cemdisiran;Inclisiran;ALN-PCSsc;Cemdisiran, terminal sugar modification-;Inclisiran, terminal sugar modification-
SMILESP(=O)(O)(O)OC[C@@H]1C[C@H](CN1C(CCCCCCCCCCC(NC(COCCC(NCCCNC(CCCCO[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)NC(C)=O)=O)=O)=O)=O)O
FormulaC78H140N11O34P
M.Wt1806.97328567505
Purity>95%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationsiRNA/ASOs/Aptamer drugs
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg5.5341 mL1.1068 mL0.5534 mL
25 mg13.8353 mL2.7671 mL1.3835 mL
50 mg27.6706 mL5.5341 mL2.7671 mL
100 mg55.3412 mL11.0682 mL5.5341 mL
250 mg138.3529 mL27.6706 mL13.8353 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.