| CAS No. | Not available |
| Chemical Name | DSPE-PEG-OPSS |
| Synonyms | Not available |
| SMILES | CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(=O)(O)OCCNC(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCSSC1=CC=CC=N1)OC(=O)CCCCCCCCCCCCCCCCC |
| Formula | C127H245O49N2PS2 |
| M.Wt | 2679.42 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | Functionalized Lipids |

DSPE-PEG-OPSS
Description & Application
DSPE-PEG-OPSS, DSPE (1,2-distearoyl-sn-glycerol-3-phosphoethanolamine) is a saturated 18 carbon phospholipid, commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification. The PEG of phospholipid significantly improved the blood circulation time and stability of the capsule drug. Polyethylene glycol can enhance the solubility and stability, reduce the non-specific binding of charged molecules on the surface, and reduce the immunogenicity of polypeptides. Mercaptopyridine reacts with mercapto group to release pyridine ring and generate stable disulfide bond.
Solution Calculators
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Quick preparation table
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 3.7322 mL | 0.7464 mL | 0.3732 mL |
| 25 mg | 9.3304 mL | 1.8661 mL | 0.9330 mL |
| 50 mg | 18.6608 mL | 3.7322 mL | 1.8661 mL |
| 100 mg | 37.3215 mL | 7.4643 mL | 3.7322 mL |
| 250 mg | 93.3038 mL | 18.6608 mL | 9.3304 mL |
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