GalNAc-L96 Linker-Acid
DC66555
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GalNac-L96, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs[1].
| CAS No. | 1159408-62-4 |
| Chemical Name | Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester, compd. with N,N-diethylethanamine (1:1) |
| Synonyms | Not available |
| SMILES | C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@@H]1C[C@@H](OC(=O)CCC(=O)O)CN1C(=O)CCCCCCCCCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1NC(=O)C)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1NC(=O)C)COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](COC(=O)C)[C@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1NC(=O)C.CCN(CC)CC |
| Formula | C127H194N12O45 |
| M.Wt | 2608.95270013809 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | 1. Anna Clua, et al. Properties of Parallel Tetramolecular G-Quadruplex Carrying N-Acetylgalactosamine as Potential Enhancer for Oligonucleotide Delivery to Hepatocytes. Molecules. 2022 Jun 20;27(12):3944. |
| Product classification | Galnac Molecules · siRNA Delivery |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 3.8330 mL | 0.7666 mL | 0.3833 mL |
| 25 mg | 9.5824 mL | 1.9165 mL | 0.9582 mL |
| 50 mg | 19.1648 mL | 3.8330 mL | 1.9165 mL |
| 100 mg | 38.3296 mL | 7.6659 mL | 3.8330 mL |
| 250 mg | 95.8239 mL | 19.1648 mL | 9.5824 mL |
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