For research use only. We do not sell to patients.
PEGylated lipids / ALC-0159
ALC-0159 chemical structure
CAT. NO. DC52020Featured

ALC-0159

Pack size & price

USD
TotalUS$200
Ships from ShanghaiFor research use only
Product overview

Description & Application

ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid). Formulations containing ALC-0159 have been used in the development of lipid nanoparticles (LNPs) for the delivery of mRNA-based vaccines.

CAS No.1849616-42-7
Chemical NameALC-0159 (di-C18)
SynonymsALC-0159;ALC 0159;ALC0159
SMILESO=C(N(CCCCCCCCCCCCCCC)CCCCCCCCCCCCCC)COCCOC
Formula(C2H4O)NC31H63NO2
M.Wt2400.24
Purity>99%
Storage-20°C, protect from light
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationPublic Assessment Report Authorisation for Temporary Supply COVID-19 mRNA Vaccine BNT162b2 (BNT162b2 RNA) concentrate for solution for injection"""" (PDF). Regulation 174. MHRA. 15 December 2020.
Product classificationPEGylated lipids
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg4.1663 mL0.8333 mL0.4166 mL
25 mg10.4156 mL2.0831 mL1.0416 mL
50 mg20.8313 mL4.1663 mL2.0831 mL
100 mg41.6625 mL8.3325 mL4.1663 mL
250 mg104.1563 mL20.8313 mL10.4156 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: -20°C, protect from light
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.