Inclisiran
DC47292
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Miravirsen (SPC-3649), a β-d-oxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide, inhibit the biogenesis of miR-122. Miravirsen (SPC-3649) is used in the study for HCV infections.
| CAS No. | 1072874-90-8 |
| Chemical Name | Miravirsen |
| Synonyms | Miravirsen;Miravirsen [INN];SPC3649 Parent Acid;Q083AJW7VS;RNA, (P-thio)((2'-O,4'-C-methylene)m5C-dC-(2'-O,4'-C-methylene)A-dT-dT-(2'-O,4'-C-methylene)G-(2'-O,4'-C-methylene)m5U-dC-dA-(2'-O,4'-C-methylene)m5C-dA-(2'-O,4'-C-methylene)m5C-dT-(2'-O,4'-C-methylene)m5C-(2'-O,4'-C-methylene)m5C) |
| SMILES | S=P(O)(OCC12COC(C(N3C(NC(C(C)=C3)=O)=O)O1)C2OP(O)(OCC1C(CC(N2C(N=C(C=C2)N)=O)O1)OP(O)(OCC1C(CC(N2C=NC3C(N)=NC=NC2=3)O1)OP(O)(OCC12COC(C(N3C(N=C(C=C3)N)=O)O1)C2OP(O)(OCC1C(CC(N2C=NC3C(N)=NC=NC2=3)O1)OP(O)(OCC12COC(C(N3C(N=C(C=C3)N)=O)O1)C2OP(O)(OCC1C(CC(N2C(NC(C(C)=C2)=O)=O)O1)OP(O)(OCC12COC(C(N3C(N=C(C=C3)N)=O)O1)C2OP(O)(OCC12COC(C(N3C(N=C(C=C3)N)=O)O1)C2O)=S)=S)=S)=S)=S)=S)=S)=S)OC1C2C(N3C=NC4C(NC(N)=NC3=4)=O)OC1(COP(O)(OC1CC(N3C(NC(C(C)=C3)=O)=O)OC1COP(O)(OC1CC(N3C(NC(C(C)=C3)=O)=O)OC1COP(O)(OC1C3C(N4C=NC5C(N)=NC=NC4=5)OC1(COP(O)(OC1CC(N4C(N=C(C=C4)N)=O)OC1COP(O)(OC1C4C(N5C(N=C(C=C5)N)=O)OC1(CO)CO4)=S)=S)CO3)=S)=S)=S)CO2 |
| Formula | C151H185N49O83P14S14 |
| M.Wt | 4896.90576338768 |
| Purity | >95% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | siRNA/ASOs/Aptamer drugs |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 2.0421 mL | 0.4084 mL | 0.2042 mL |
| 25 mg | 5.1053 mL | 1.0211 mL | 0.5105 mL |
| 50 mg | 10.2105 mL | 2.0421 mL | 1.0211 mL |
| 100 mg | 20.4211 mL | 4.0842 mL | 2.0421 mL |
| 250 mg | 51.0526 mL | 10.2105 mL | 5.1053 mL |
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