Tofersen (BIIB067) is an antisense oligonucleotide that mediates RNase H-dependent degradation of superoxide dismutase 1 (SOD1) mRNA to reduce the synthesis of SOD1 protein. Tofersen can be used for the research of amyotrophic lateral sclerosis (ALS).
| CAS No. | 2088232-70-4 |
| Chemical Name | Tofersen |
| Synonyms | BIIB067; ISIS-SOD1Rx |
| SMILES | Not available |
| Formula | Not available |
| M.Wt | 7128.00 |
| Purity | >95% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | Not available |
| Product classification | siRNA/ASOs/Aptamer drugs |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 1.4029 mL | 0.2806 mL | 0.1403 mL |
| 25 mg | 3.5073 mL | 0.7015 mL | 0.3507 mL |
| 50 mg | 7.0146 mL | 1.4029 mL | 0.7015 mL |
| 100 mg | 14.0292 mL | 2.8058 mL | 1.4029 mL |
| 250 mg | 35.0730 mL | 7.0146 mL | 3.5073 mL |
Contact our team with the catalog number and requested quantity.