GalNAc-L96 Linker-Acid
DC66555
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tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research.
| CAS No. | 1953146-81-0 |
| Chemical Name | tri-GalNAc-COOH |
| Synonyms | 4,11,14,17,20,23-Hexaoxa-7-azapentacosanamide, N-[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]-6,6-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-25-hydroxy-8-oxo-;SGN-46810;tri-GalNAc-COOH |
| SMILES | C(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(=O)C)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(=O)C)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(=O)C)NC(=O)CCOCCOCCOCCOCCOCCC(=O)O |
| Formula | C75H134N10O35 |
| M.Wt | 1735.91 |
| Purity | >95% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | 1. Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506. |
| Product classification | Galnac Molecules · siRNA Delivery |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 5.7607 mL | 1.1521 mL | 0.5761 mL |
| 25 mg | 14.4017 mL | 2.8803 mL | 1.4402 mL |
| 50 mg | 28.8033 mL | 5.7607 mL | 2.8803 mL |
| 100 mg | 57.6067 mL | 11.5213 mL | 5.7607 mL |
| 250 mg | 144.0167 mL | 28.8033 mL | 14.4017 mL |
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