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Adjuvant molecules / Polyinosinic-polycytidylic acid sodium
Polyinosinic-polycytidylic acid sodium chemical structure
CAT. NO. DC28932Featured

Polyinosinic-polycytidylic acid sodium

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Ships from ShanghaiFor research use only
Product overview

Description & Application

Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.

CAS No.42424-50-0
Chemical NamePolyinosinic-polycytidylic acid sodium
SynonymsPoly I:C
SMILESO[C@H]1[C@@H](O[C@H](COP(O)(O)=O)[C@H]1O)N2C3=C(C(NC=N3)=O)N=C2.O[C@H]4[C@H](N5C(N=C(N)C=C5)=O)O[C@H](COP(O)(O)=O)[C@H]4O.[x].[x].[Na].[x]
Formula(C10H13N4O8P)X.(C9H14N3O8P)X.XNa
M.Wt0
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationAdjuvant Molecules
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
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C₁V₁ = C₂V₂
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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.