DC Chemicals · Product datasheet

G6PD activator AG1 · DC12438

AG1 is a small-molecule G6PD activator for enzyme oligomerization, NADPH metabolism and redox research.

ParameterValue
Chemical Name2,2'-disulfanediylbis(N-(2-(1H-indol-3-yl)ethyl)ethan-1-amine)
CAS No.421581-52-4
SynonymsAG1; AG-1,AG 1
FormulaC24H30N4S2
M.Wt438.652
SMILESS(CCNCCC1C2=C(NC=1)C=CC=C2)SCCNCCC1C2=C(NC=1)C=CC=C2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

AG1 is a small-molecule G6PD activator for enzyme oligomerization, NADPH metabolism and redox research.

View referenced In Vitro and In Vivo results on the product page

References

  1. Raub AG, et al. Small-Molecule Activators of Glucose-6-phosphate Dehydrogenase (G6PD) Bridging the Dimer Interface. ChemMedChem (2019).
  2. Hwang S, et al. Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator. Nature Communications 9, 4045 (2018).

Available packs

  • 10mg · US$550
  • 25mg · US$950
  • 100mg · US$1,650
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