DC Chemicals · Product datasheet

JP-153 · DC11954

JP-153 is a focal-adhesion-signaling modulator for VEGF-dependent retinal endothelial-cell and angiogenesis research.

ParameterValue
Chemical Name4-(3,4,5-trimethoxyphenyl)-1,4-dihydro-2H-naphtho[1,2-d][1,3]oxazin-2-one
CAS No.1802937-26-3
SynonymsJP 153; JP153
FormulaC21H19NO5
M.Wt365.385
SMILESO1C(C2=CC(OC)=C(OC)C(OC)=C2)C2=CC=C3C(=C2NC1=O)C=CC=C3
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

JP-153 is a focal-adhesion-signaling modulator for VEGF-dependent retinal endothelial-cell and angiogenesis research.

View referenced In Vitro and In Vivo results on the product page

References

  1. Toutounchian JJ, et al. Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis. Molecular pharmacology (2017).

Available packs

  • 10 mg · US$500
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