DC Chemicals · Product datasheet
CK-869 · DC11475
CK-869 is an Arp2/3 complex inhibitor for branched-actin and cytoskeletal research, with reported microtubule-related off-target effects.
| Parameter | Value |
|---|---|
| Chemical Name | 2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one |
| CAS No. | 388592-44-7 |
| Synonyms | 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one; CK 869; 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone; CK-0157869; CK-869 |
| Formula | C17H16BrNO3S |
| M.Wt | 394.28284 |
| SMILES | O=C1N(C2=CC=C(OC)C=C2OC)C(C3=CC=CC(Br)=C3)SC1 |
| Purity | On request |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Biological activity summary
CK-869 is an Arp2/3 complex inhibitor for branched-actin and cytoskeletal research, with reported microtubule-related off-target effects.
View referenced In Vitro and In Vivo results on the product pageReferences
- Hetrick B, et al. Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chemistry & biology (2013).
- Use of CK-548 and CK-869 as Arp2/3 complex inhibitors directly suppresses microtubule assembly both in vitro and in vivo. Biochemical and biophysical research communications (2018).
Available packs
- 100 mg · US$650
- 250 mg · US$1,000
- 1 g · US$1,900
- 10 mM * 1 mL in DMSO · US$220