DC Chemicals · Product datasheet

SEC inhibitor KL-2 · DC11392

KL-2 is a small-molecule disruptor of the super elongation complex for transcriptional elongation and MYC-dependent cancer research.

ParameterValue
Chemical NameN-(5-chloro-2-methylphenyl)-4-(4-fluorophenyl)-2,4-dioxobutanamide
CAS No.900308-51-2
SynonymsKL2,KL-2,KL 2
FormulaC17H13ClFNO3
M.Wt333.06
SMILESC1=CC(F)=CC=C1C(CC(C(=O)NC1=CC(Cl)=CC=C1C)=O)=O
PurityOn request
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

KL-2 is a small-molecule disruptor of the super elongation complex for transcriptional elongation and MYC-dependent cancer research.

View referenced In Vitro and In Vivo results on the product page

References

  1. Liang K, et al. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy. Cell (2018).

Available packs

  • 100 mg · US$650
  • 250 mg · US$1,100
  • 1g · US$2,200
  • 10 mM * 1 mL in DMSO · US$220
View product and biological activity →

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