DC Chemicals · Product datasheet

OTS186935 · DC11257

OTS186935 is a SUV39H2 inhibitor with published cellular and xenograft activity, used in histone-methylation and cancer research.

ParameterValue
Chemical Name(S)-1-(2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl)-N-(pyridin-4-ylmethyl)pyrrolidin-3-amine
CAS No.2093400-18-9
SynonymsOTS-186935; OTS 186935
FormulaC25H26ClN5O2
M.Wt463.966
SMILESN(C1C=CN2C=C(C3=CC(Cl)=C(OC)C=C3OC)N=C2C=1)1CC[C@@H](NCC2C=CN=CC=2)C1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

OTS186935 is a SUV39H2 inhibitor with published cellular and xenograft activity, used in histone-methylation and cancer research.

View referenced In Vitro and In Vivo results on the product page

References

  1. Vougiouklakis T, et al. Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX. Oncotarget (2018).

Available packs

  • 10 mg · US$600
  • 25 mg · US$1,050
  • 100 mg · US$1,900
View product and biological activity →

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