DC Chemicals · Product datasheet
BAY-3827 · DC10978
BAY-3827 is an AMPK inhibitor with additional RSK-family activity, used to study metabolic signaling and androgen-dependent prostate cancer.
| Parameter | Value |
|---|---|
| Chemical Name | BAY-3827 |
| CAS No. | 2377576-35-5 |
| Synonyms | Benzamide, N-[5-(3,5-dicyano-1,4-dihydro-1,2,6-trimethyl-4-pyridinyl)-6-fluoro-7-methyl-1H-indazol-3-yl]-2-ethyl-; BAY-3827 |
| Formula | C27H25FN6O |
| M.Wt | 468.53 |
| SMILES | C(NC1C2=C(NN=1)C(C)=C(F)C(C1C(C#N)=C(C)N(C)C(C)=C1C#N)=C2)(=O)C1=CC=CC=C1CC |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Biological activity summary
BAY-3827 is an AMPK inhibitor with additional RSK-family activity, used to study metabolic signaling and androgen-dependent prostate cancer.
View referenced In Vitro and In Vivo results on the product pageReferences
- Lemos C, et al. The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models. Cellular oncology (Dordrecht, Netherlands) (2021).
- BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation. International journal of molecular sciences (2023).
Available packs
- 100mg · US$600
- 250mg · US$1,100
- 1g · US$2,200