DC Chemicals · Product datasheet

KML-29 · DC10536

KML-29 is a selective MAGL inhibitor used to investigate endocannabinoid metabolism, inflammatory pain and neuropathic pain.

Parameter	Value
Chemical Name	KML-29
CAS No.	1380424-42-9
Synonyms	KML29; KML 29; 1,1,1,3,3,3-Hexafluoro-2-propanyl 4-[bis(1,3-benzodioxol-5-yl)(hy droxy)methyl]-1-piperidinecarboxylate; 1,1,1,3,3,3-hexafluoroisopropylacrylate; 1,1,1,3,3,3-hexafluoroprop-2-yl acrylate; 1,1,1,3,3,3-hexafluoropropan-2-yl acrylate; Acrylic Acid 1,1,1,3,3,3-Hexafluoroisopropyl Ester; hexafluoro-2-propyl acrylate; Hexafluoroisopropyl acrylate; 4-[bis(1,3-Benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester; 1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate; SXHQLPHDBLTFPM-UHFFFAOYSA-N; GTPL9482; BDBM179929; BCP16466; US9133148, 1a; AK547299; 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate; 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(bis(benzo[d][1,3]dioxol-5-yl)(hydroxy)methyl)piperidine-1-carboxylate; 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic acid 2,2,2-triflu
Formula	C24H21F6NO7
M.Wt	549.4165
SMILES	FC(C([H])(C(F)(F)F)OC(N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C(C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])O2)(C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])O2)O[H])=O)(F)F
Purity	On request
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

KML-29 is a selective MAGL inhibitor used to investigate endocannabinoid metabolism, inflammatory pain and neuropathic pain.