DC Chemicals · Product datasheet
NCT-503 · DC10486
NCT-503 is a PHGDH inhibitor for studying serine synthesis, one-carbon metabolism and metabolic dependencies in cancer models. Published studies distinguish biochemical inhibition from cellular growth effects and document context-dependent off-target activity.
| Parameter | Value |
|---|---|
| Chemical Name | N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide |
| CAS No. | 1916571-90-8 |
| Synonyms | NCT 503,NCT503 |
| Formula | C20H23F3N4S |
| M.Wt | 408.48 |
| SMILES | S=C(N1CCN(CC2=CC=C(C(F)(F)F)C=C2)CC1)NC3=NC(C)=CC(C)=C3 |
| Purity | >98% |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Available packs
- 100 mg · US$500
- 250 mg · US$850
- 1 g · US$1,700
- 10 mM * 1 mL in DMSO · US$220