DC Chemicals · Product datasheet

Mavacamten (MYK-461) · DC11524

Mavacamten (MYK-461) is a cardiac myosin inhibitor used to study sarcomere contractility and hypertrophic cardiomyopathy.

Parameter	Value
Chemical Name	Mavacamten
CAS No.	1642288-47-8
Synonyms	Mavacamten; QX45B99R3J; (S)-3-isopropyl-6-((1-phenylethyl)amino)pyrimidine-2,4(1H,3H)-dione; Mavacamten [INN]; Mavacamten [WHO-DD]; MYK461; GTPL11265; s8861; SAR439152; DB14921; SB19779; (S)-3-Isopropyl-6-((1-phenylethyl)amino) pyrimidine-2,4(1H,3H)-dione; (S)-3-Isopropyl-6-((1-phenylethyl)amino)pyrimidine-2, 4(1H,3H)-dione; (S)-3-Isopropyl-6
Formula	C15N3O2H19
M.Wt	273.3303
SMILES	O=C1N([H])C(=C([H])C(N1C([H])(C([H])([H])[H])C([H])([H])[H])=O)N([H])[C@@]([H])(C([H])([H])[H])C1C([H])=C([H])C([H])=C([H])C=1[H]
Purity	98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

Mavacamten (MYK-461) is a cardiac myosin inhibitor used to study sarcomere contractility and hypertrophic cardiomyopathy.