DC Chemicals · Product datasheet

ABC 1183 · DC11299

ABC 1183 (ABC1183) is a dual GSK-3/CDK9 inhibitor for cancer-cell proliferation and inflammatory signaling research.

ParameterValue
Chemical Name4-(4-Amino-2-p-tolylamino-thiazole-5-carbonyl)-benzonitrile
CAS No.1042735-18-1
SynonymsABC1183; ABC-1183; ABC 1183
FormulaC18H14N4OS
M.Wt334.397
SMILESN#CC1=CC=C(C(C2=C(N)N=C(NC3=CC=C(C)C=C3)S2)=O)C=C1
PurityOn request
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

ABC 1183 (ABC1183) is a dual GSK-3/CDK9 inhibitor for cancer-cell proliferation and inflammatory signaling research.

View referenced In Vitro and In Vivo results on the product page

References

  1. Schrecengost RS, et al. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183. The Journal of pharmacology and experimental therapeutics (2018).

Available packs

  • 100 mg · US$950
  • 10 mM * 1 mL in DMSO · US$220
View product and biological activity →

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