DC Chemicals · Product datasheet

PF-543 · DC1107

PF-543 is a potent, sphingosine-competitive SPHK1 inhibitor for investigating S1P production and sphingolipid signaling.

ParameterValue
Chemical NamePF-543 free base
CAS No.1415562-82-1
SynonymsPF543, PF 543
FormulaC27H31NO4S
M.Wt465.608
SMILESN(CC1=CC=C(COC2=CC(CS(C3=CC=CC=C3)(=O)=O)=CC(C)=C2)C=C1)1CCC[C@H]1CO
PurityOn request
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

PF-543 is a potent, sphingosine-competitive SPHK1 inhibitor for investigating S1P production and sphingolipid signaling.

View referenced In Vitro and In Vivo results on the product page

References

  1. Schnute ME, et al. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. The Biochemical journal (2012).

Available packs

  • 100 mg · US$400
  • 250 mg · US$800
  • 1 g · US$1,600
  • 10 mM * 1 mL in DMSO · US$150
View product and biological activity →

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