DC Chemicals · Product datasheet
SW076956 · DC10965
SW076956 is an early BCL-2/Beclin 1 interaction inhibitor used in autophagy-modulation research.
| Parameter | Value |
|---|---|
| Chemical Name | N-(4-(5-(furan-2-yl)-1-(4-methylbenzoyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide |
| CAS No. | 851717-83-4 |
| Synonyms | SW-076956,SW 076956 |
| Formula | C22H21N3O4S |
| M.Wt | 423.487 |
| SMILES | CS(NC1=CC=C(C2CC(C3=CC=CO3)N(C(=O)C3=CC=C(C)C=C3)N=2)C=C1)(=O)=O |
| Purity | On request |
| Storage | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Biological activity summary
SW076956 is an early BCL-2/Beclin 1 interaction inhibitor used in autophagy-modulation research.
View referenced In Vitro and In Vivo results on the product pageReferences
- Dong X, et al. Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2-Beclin 1 Protein-Protein Interaction. ACS medicinal chemistry letters (2022).
- Chiang WC, et al. High Throughput Screens to Identify Autophagy Inducers that Function by Disrupting Beclin 1/Bcl-2 Binding. ACS Chemical Biology (2018).
Available packs
- 10 mg · US$400
- 25 mg · US$600
- 50 mg · US$900