DC Chemicals · Product datasheet

PH-002 · DC10794

PH-002 is an ApoE4 structure-correcting research compound studied in human iPSC-derived neurons with Alzheimer-related phenotypes.

ParameterValue
Chemical Name4-[[4-[[2-(3,4-Dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
CAS No.1311174-68-1
SynonymsPH002,PH-002,PH 002
FormulaC27H33N5O4
M.Wt491.58
SMILESN(C(OC(C)(C)C)=O)1CCN(CC2=CC=C(NC(CC3C4=C(C=CC=C4)C(=O)N(C)N=3)=O)C=C2)CC1
PurityOn request
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity summary

PH-002 is an ApoE4 structure-correcting research compound studied in human iPSC-derived neurons with Alzheimer-related phenotypes.

View referenced In Vitro and In Vivo results on the product page

References

  1. Wang C, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nature medicine (2018).

Available packs

  • 100 mg · US$750
  • 250 mg · US$1,200
  • 1 g · US$2,500
  • 10 mM * 1 mL in DMSO · US$220
View product and biological activity →

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