DC Chemicals · Product datasheet

ARV-771 · DC10334

ARV-771 is a VHL-recruiting BET protein degrader for prostate cancer and targeted protein degradation research. The primary study reports pan-BET degradation, downstream c-MYC suppression and activity in prostate cancer models.

ParameterValue
Chemical NameARV 771; ARV771
CAS No.1949837-12-0
SynonymsARV 771; ARV771
FormulaC49H60ClN9O7S2
M.Wt986.64
SMILESCC(C(C(C1=CC=C(Cl)C=C1)=N[C@@H](CC(NCCOCCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C2)[C@@H]2C(N[C@H](C3=CC=C(C(SC=N4)=C4C)C=C3)C)=O)=O)=O)=O)C5=NN=C(C)N65)=C6S7)=C7C
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Available packs

  • 100 mg · US$600
  • 250 mg · US$1,100
  • 1 g · US$2,200
  • 10 mM * 1 mL in DMSO · US$220
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