DC Chemicals

DC67521 · Updated 28 October 2026

Lipid TD5

Instructions for Use

Before use

Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year. In solvent: −80 °C, 6 months; −20 °C, 1 month. Keep sealed and protected from light.

For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.

Stock-solution planning

Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].

Mass10 mM20 mM
10 mg1.4702 mL0.7351 mL
25 mg3.6756 mL1.8378 mL
50 mg7.3512 mL3.6756 mL
100 mg14.7024 mL7.3512 mL

Literature formulation reference

ComponentDC Chemicals productMolecular weightMolar ratioMass at 1 µmol total lipid (mg)
TD5DC67521680.16Not assignedNot calculable from disclosed data
DOPEDC33634744.03Not assignedNot calculable from disclosed data
CholesterolDCD-041386.65Not assignedNot calculable from disclosed data
DMG-PEG2000DC401692507Not assignedNot calculable from disclosed data

The paper identifies TD5, DOPE, cholesterol and DMG-PEG2000. Complete preparation Methods are in the Supporting Information, which was not accessible for this review. Quantitative molar ratios, N/P and lipid:RNA mass ratio could not be verified from the accessible full manuscript and are left unassigned.

Read the complete study conditions, biological results, tolerability and figures →

References

  1. Xue Y, Wang C, Li H, et al. Lipid Nanoparticles Enhance mRNA Delivery to the Central Nervous System Upon Intrathecal Injection. Advanced Materials 37, 2417097 (2025). DOI: 10.1002/adma.202417097.
  2. Full author manuscript: Figures 2–6.