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VY-3-135
CAT. NO. DC71165

VY-3-135

Pack sizes and prices

Pack sizePrice
100mg$800 USDRequest a quote / confirm availability →
250mg$1,450 USDRequest a quote / confirm availability →
1g$2,800 USDRequest a quote / confirm availability →

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Product overview

VY-3-135 is an orally active, selective acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 value of 44 nM. VY-3-135 displayes no inhibitory activity towards recombinant human ACSS1 or ACSS3. VY-3-135 potently inhibits ACSS2 dependent fatty acid metabolism but has no effect on gene expression in tumors. VY-3-135 inhibits triple negative breast cancer (TNBC) tumor growth in mouse ACSS2high but not ACSS2low tumors models.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC71165
Product nameVY-3-135
CAS1824637-41-3
Molecular formulaC26H27N3O3
Molecular weight429.51
Purity98%
SMILESCCn1c(C(O)(c2ccccc2)c2ccccc2)nc2ccc(C(=O)NC[C@@H](C)O)cc21

Source-listed specifications; the batch COA applies.

Source and product documents

The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.

DC Chemicals — VY-3-135 (DC71165)

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