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XD2-149
CAT. NO. DC53120

XD2-149

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Pack sizePrice
100mg$3,000 USDRequest a quote / confirm availability →

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Product overview

XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC53120
Product nameXD2-149
Molecular formulaC38H39N5O8
Molecular weight693.757
Purity>98%
SMILESO=C1CCC(N2C(=O)c3cccc(NCCCCCC4CCN(CCNC(=O)c5cc6c(o5)C(=O)c5ccccc5C6=O)CC4)c3C2=O)C(=O)N1

Source-listed specifications; the batch COA applies.

Source and product documents

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DC Chemicals — XD2-149 (DC53120)

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