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HEC96719
CAT. NO. DC60775

HEC96719

Pack sizes and prices

Pack sizePrice
5mg$450 USDRequest a quote / confirm availability →
25mg$1,500 USDRequest a quote / confirm availability →
10mg$750 USDRequest a quote / confirm availability →

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Product overview

HEC96719 is a tricyclic farnesoid X receptor agonist (FXR agonist) for treatment of non-alcoholic steatohepatitis. HEC96719 exhibits excellent potency superior to GW4064 and obeticholic acid in in vitro and in vivo assays of FXR activation. It also shows higher FXR selectivity and more favorable tissue distribution dominantly in liver and intestine. Preclinical data on pharmacokinetic properties, efficacy, and safety profiles overall indicate that HEC96719 is a promising drug candidate for NASH treatment.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC60775
Product nameHEC96719
CAS2181834-03-5
Molecular formulaC29H22Cl2N2O5
Molecular weight549.404
Purity98%
SMILESO=C(O)c1ccc2c(c1)Oc1ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)nc1C1(CC1)C2

Source-listed specifications; the batch COA applies.

Source and product documents

The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.

DC Chemicals — HEC96719 (DC60775)

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