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ARCC-4
CAT. NO. DC40420

ARCC-4

Pack sizes and prices

Pack sizePrice
100mg$950 USDRequest a quote / confirm availability →
250mg$1,700 USDRequest a quote / confirm availability →
1g$3,800 USDRequest a quote / confirm availability →

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Product overview

ARCC-4 is a low-nanomolar androgen receptor (AR) degrader based on PROTAC, with a DC50 of 5?nM. ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC40420
Product nameARCC-4
CAS1973403-00-7
Molecular formulaC53H56F3N7O7S2
Molecular weight1024.18
SMILESCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCCCOc2ccc(-c3ccc(N4C(=S)N(c5ccc(C#N)c(C(F)(F)F)c5)C(=O)C4(C)C)cc3)cc2)C(C)(C)C)cc1

Source-listed specifications; the batch COA applies.

Source and product documents

The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.

DC Chemicals — ARCC-4 (DC40420)

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