DC Chemicals

DC67567 · Updated 28 October 2026

ARV-T1

Product Datasheet

ARV-T1 is an ionizable lipid investigated for intramuscular mRNA delivery. Its research LNP formulation showed prolonged reporter expression and enhanced antibody responses relative to the study SM-102 comparator, with supporting cell-viability and short-term mouse tolerability data.

CAS No.Not available
Chemical NameARV-T1
SynonymsARVT1, ARV T1
SMILESCCCCCCCCC(CCCCCC)OC(=O)CCCCCCN(CCCCO)CCCCCC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2[C@H](C)CCCC(C)C)C1
FormulaC59H107NO5
M.Wt910.51
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. Jeon JH, et al. Lipid Nanoparticles Formulated with a Novel Cholesterol-Tailed Ionizable Lipid Markedly Increase mRNA Delivery Both in vitro and in vivo. International Journal of Nanomedicine 20, 9389–9405 (2025). DOI: 10.2147/IJN.S527822.
  2. Full text: formulation Methods and Figures 2–7.

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.