DC67567 · Updated 28 October 2026
ARV-T1
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 1.0983 mL | 0.5491 mL |
| 25 mg | 2.7457 mL | 1.3729 mL |
| 50 mg | 5.4914 mL | 2.7457 mL |
| 100 mg | 10.9829 mL | 5.4914 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| ARV-T1 | DC67567 | 910.51 | 50 | 0.455255 |
| DSPC | DC57005 | 790.15 | 10 | 0.079015 |
| Cholesterol | DCD-041 | 386.65 | 38.5 | 0.148860 |
| DMG-PEG2000 | DC40169 | 2507 | 1.5 | 0.037605 |
ARV-T1/DSPC/cholesterol/DMG-PEG2000 = 50:10:38.5:1.5 mol%; reported N/P = 4. Source: Methods, LNP formulation. DMG-PEG2000 uses 2507 for calculated component masses. A lipid:RNA mass ratio is not inferred from N/P.
Read the complete study conditions, biological results, tolerability and figures →