PRODUCT DATASHEET · DC67558
AMG1541
Product Datasheet
Version 1.b9c0a92c · 2026-09-15
| CAS No. | Not available |
| Chemical Name | AMG1541 |
| Synonyms | AMG-1541，AMG 1541 |
| SMILES | CCCCCC/C=C\CCCC(=O)OCC(O)CN1CCN(CC(O)COC(=O)CCC/C=C\CCCCCC)CCN(CC(O)COC(=O)CCC/C=C\CCCCCC)CCN(CC(O)COC(=O)CCC/C=C\CCCCCC)CCN(CC(O)COC(=O)CCC/C=C\CCCCCC)CCN(CC(O)COC(=O)CCC/C=C\CCCCCC)CC1 |
| Formula | C102H186O18N6 |
| M.Wt | 1,783.38 |
| Purity | ELSD-HPLC>95% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Rudra A, Gupta A, Reed K, et al. Degradable cyclic amino alcohol ionizable lipids as vectors for potent influenza mRNA vaccines. Nature Nanotechnology. 2025;20:1831–1842. |
AMG1541 is a degradable hexacyclen-based ionizable lipid evaluated for intramuscular mRNA delivery and influenza vaccination in mice. Its reported DOPE-containing LNP formulation improved reporter expression and antibody responses relative to an SM-102 reference formulation. The magnitude of benefit depends on the assay, formulation, dose and mouse strain.
Specifications shown are product-page values, not batch test results.
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