DC60809 · Updated 28 October 2026
6Ac1-C12
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 0.5634 mL | 0.2817 mL |
| 25 mg | 1.4086 mL | 0.7043 mL |
| 50 mg | 2.8171 mL | 1.4086 mL |
| 100 mg | 5.6342 mL | 2.8171 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| 6Ac1-C12 | DC60809 | 1774.86 | 15 | 0.429402 |
| DOPE | DC33634 | 744.03 | 20 | 0.240010 |
| Cholesterol | DCD-041 | 386.65 | 25 | 0.155907 |
| DMG-PEG2000 | DC40169 | 2507 | 2 | 0.080871 |
Relative molar parts, not percentages. 6Ac1-C12:mRNA mass ratio 10:1; this is not total lipid:mRNA or N/P. Main p.9; SI pp.2–4. DMG-PEG2000 uses 2507 for the catalog conversion.
Read the complete study conditions, biological results, tolerability and figures →
