DC59002 · Updated 28 October 2026
ssPalmO-Phe
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 0.8520 mL | 0.4260 mL |
| 25 mg | 2.1299 mL | 1.0649 mL |
| 50 mg | 4.2598 mL | 2.1299 mL |
| 100 mg | 8.5195 mL | 4.2598 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| ssPalmO-Phe | DC59002 | 1173.777 | 70 | 0.809501 |
| Cholesterol | DCD-041 | 386.65 | 30 | 0.114281 |
| DMG-PEG2000 | DC40169 | 2507 | 1.5 | 0.037049 |
siRNA formulation: ssPalmO-Phe/cholesterol = 70:30 with an additional 1.5 parts DMG-PEG2000; lipid/siRNA = 400 nmol/µg. The displayed 70:30:1.5 parts are normalized only for mass calculations. The 400 nmol/µg value is neither a weight ratio nor N/P. ASO uses the separate four-component composition below.
Read the complete study conditions, biological results, tolerability and figures →