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Ncrw0005-f05
CAT. NO. DCC3590

Ncrw0005-f05

Pack sizes and prices

Pack sizePrice
100 mg$850 USDRequest a quote / confirm availability →
250 mg$1,350 USDRequest a quote / confirm availability →
1 g$2,800 USDRequest a quote / confirm availability →

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Product overview

NCRW0005-F05 is a small-molecule inhibitor reported to target the Wnt/β-catenin signaling pathway with activity in vitro. It suppresses β-catenin–dependent transcription in a concentration-dependent manner, with reported IC50 values in the low micromolar range (~1–10 µM) in reporter assays. NCRW0005-F05 reduces expression of Wnt target genes such as c-Myc and cyclin D1, leading to decreased proliferation in Wnt-driven cancer cell models.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDCC3590
Product nameNcrw0005-f05
CAS342779-66-2
Molecular formulaC16H13F2NO2
Molecular weight289.28
Purity>98%
SMILESCOc1ccc(C2N(c3ccccc3)C(=O)C2(F)F)cc1

Source-listed specifications; the batch COA applies.

Source and product documents

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DC Chemicals — Ncrw0005-f05 (DCC3590)

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