All products / DC28539
CAT. NO. DC28539
SIAIS178
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100mg | $1,100 USDRequest a quote / confirm availability → |
| 250mg | $1,900 USDRequest a quote / confirm availability → |
| 1g | $3,950 USDRequest a quote / confirm availability → |
Confirm stock, lead time, shipping and final quotation with our team.
Product overview
SIAIS178 is a potent and selective BCR-ABL degrader based on PROTAC technology with an IC50 of 24 nM. SIAIS178 causes effective degradation of BCR-ABL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. SIAIS178 has anticancer activity.
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC28539 |
|---|---|
| Product name | SIAIS178 |
| CAS | 2376047-73-1 |
| Molecular formula | C50H62ClN11O6S2 |
| Molecular weight | 1012.68 |
| SMILES | Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(C(=O)CCCCCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(-c4scnc4C)cc3)C(C)(C)C)CC2)n1 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — SIAIS178 (DC28539)