All products / DC50038
CAT. NO. DC50038
PROTAC SGK3 degrader-1
Pack sizes and prices
| Pack size | Price |
|---|---|
| 100 mg | $850 USDRequest a quote / confirm availability → |
| 250 mg | $1,500 USDRequest a quote / confirm availability → |
| 1 g | $2,900 USDRequest a quote / confirm availability → |
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Product overview
PROTAC SGK3 degrader-1 (SGK3-PROTAC1), is a potent SKG3 degrader based on PROTAC. PROTAC SGK3 degrader-1 (0.3 μM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate).
For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.
Identity and specifications
| Catalog number | DC50038 |
|---|---|
| Product name | PROTAC SGK3 degrader-1 |
| CAS | 2381320-35-8 |
| Molecular formula | C57H73FN10O11S2 |
| Molecular weight | 1157.37833476067 |
| Purity | >98% |
| SMILES | Cc1ccc(F)c(S(=O)(=O)Nc2ccc(-c3nc(OC[C@H]4CN(CCCCCCOCCOCCOCC(=O)N[C@H](C(=O)N5C[C@H](O)C[C@H]5C(=O)NCc5ccc(-c6scnc6C)cc5)C(C)(C)C)CCO4)c4cn[nH]c4n3)cc2)c1 |
Source-listed specifications; the batch COA applies.
Source and product documents
The supplier source is linked below. Contact us for COA, SDS and batch-specific documents.
DC Chemicals — PROTAC SGK3 degrader-1 (DC50038)