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CGP-77675
CAT. NO. DC32842

CGP-77675

Pack sizes and prices

Pack sizePrice
100 mg$600 USDRequest a quote / confirm availability →
250 mg$1,100 USDRequest a quote / confirm availability →
1 g$2,200 USDRequest a quote / confirm availability →

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Product overview

CGP-77675 is a potent and selective Src family kinase (SFK) inhibitor. CGP-77675 inhibited phosphorylation of peptide substrates and autophosphorylation of purified Src (IC50: 5-20 and 40 nM, respectively). The dual inhibition of Src and GSK-3 signaling by CGP 77675 and CHIR 99021 was found to maintain mouse embryonic stem cell (mESC) self-renewal and pluripotency marker expression as efficiently as the dual inhibition of MAPK and GSK-3 by PD 0325901 and CHIR 99021.

For research use only. Results depend on experimental conditions and do not constitute a performance guarantee.

Identity and specifications

Catalog numberDC32842
Product nameCGP-77675
CAS234772-64-6
Molecular formulaC26H29N5O2
Molecular weight443.54
Purity>98%
SMILESCOc1cccc(-c2cn(-c3ccc(CCN4CCC(O)CC4)cc3)c3ncnc(N)c23)c1

Source-listed specifications; the batch COA applies.

Source and product documents

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DC Chemicals — CGP-77675 (DC32842)

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