Table 1
Component: HI-62 | Molecular weight: 851.42 | Reported molar entry: Not recovered | Calculated mass: Not calculated
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HI-62
Literature records
Search the tables and observations reproduced from the product literature guide. Rows may represent measurements, recipes or experimental context; they are not all independent experiments.
Table 1
Component: Other formulation components | Molecular weight: Not confirmed | Reported molar entry: Not recovered | Calculated mass: Not calculated
Table 2
Parameter: Mixing | Reported procedure / limitation: Earlier record: microfluidic mixing; organic:aqueous 1:3; total flow 20 mL/min. | Source: Earlier record; primary-method check pending
Table 2
Parameter: N/P | Reported procedure / limitation: Earlier record: 3–7 screened, with approximately 97% encapsulation at N/P 3. | Source: Earlier record; primary-method check pending
Table 2
Parameter: Reproduction gaps | Reported procedure / limitation: Exact helper-lipid identities and molar fractions, buffer composition/pH, purification, and formulation-to-assay mapping have not been recovered. | Source: Not filled by inference
Table 3
Measurement / batch: E21 particle size | Reported result: 89.3 ± 0.6 nm | Evidence context: Earlier record; statistical basis pending
Table 3
Measurement / batch: PDI / encapsulation | Reported result: 0.03 / 97.5% | Evidence context: Earlier record; primary-table check pending
Table 3
Measurement / batch: Apparent particle pKa | Reported result: 6.45, TNS assay | Evidence context: Earlier record; assay conditions pending
Table 4
Experiment and dose: Reporter expression Mouse; FLuc mRNA; intravenous; 5 µg per mouse | Readout and comparator: Readout: 48 h Comparator: SM-102 formulation | Result and source: Earlier record reports >1,000-fold higher expression. Animal number, organ normalization and comparator recipe require primary-source confirmation. Earlier product record; figure not re-verified
Table 4
Experiment and dose: Freeze–thaw response RNA-loaded E21; six cycles | Readout and comparator: Readout: After six cycles; temperature protocol pending Comparator: SM-102 formulation | Result and source: Earlier record reports >95% encapsulation versus a comparator change from 96% to <90%. Expression after cycling is not established here. Earlier product record; source check pending
Table 4
Experiment and dose: Tumor study TC-1 mouse model; mRNA 10 µg per dose on days 0, 5 and 10 | Readout and comparator: Readout: Response-assessment date pending Comparator: Comparator details pending | Result and source: Earlier record reports complete responses in 4/5 mice. Cargo identity, tumor schedule and response definition must be checked before protocol reuse. Earlier product record; source check pending