Lipid SG5 (DC68228)
Lipid SG5 is a dual-amine ionizable lipid developed for systemic, lung-selective mRNA delivery. Its two tertiary amines and two C16 β-hydroxy tails support stepwise protonation in the reported fSG5 LNP system. The cited preclinical study evaluated pulmonary luciferase expression, functional Cre mRNA delivery and Nrf2 mRNA delivery in an acute lung-injury model.
| CAS No. | Not available |
| Chemical Name | Lipid SG5 |
| SMILES | CCCCCCCCCCCCCCC(O)CN(CCN(C)C)CC(O)CCCCCCCCCCCCCC |
| Formula | C36H76N2O2 |
| M.Wt | 569.02 |
| Purity | >98% |
| Storage | Powder: 2 years at −20 °C. In DMSO: 2 weeks at 4 °C or 6 months at −80 °C. |
| Shipping condition | Ships from Shanghai. Contact us to confirm the appropriate transport condition for the current batch. |
| Product classification | Cationic/Ionizable Lipids; Ionizable Lipids for lung-targeted delivery |