DC68023 · Updated 28 October 2026
Lipid 1A7B13
Instructions for Use
Before use
Check the supplied lot number, batch COA, approved SDS, quantity and retest date. Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
For small quantities of viscous or oily lipid, volumetric transfer can reduce weighing losses. Confirm solvent compatibility and solubility before preparing a stock; calculated volumes do not establish solubility.
Stock-solution planning
Volume (mL) = mass (mg) × 1000 / [molecular weight × concentration (mM)].
| Mass | 10 mM | 20 mM |
|---|---|---|
| 10 mg | 0.9349 mL | 0.4674 mL |
| 25 mg | 2.3372 mL | 1.1686 mL |
| 50 mg | 4.6744 mL | 2.3372 mL |
| 100 mg | 9.3488 mL | 4.6744 mL |
Literature formulation reference
| Component | DC Chemicals product | Molecular weight | Molar ratio | Mass at 1 µmol total lipid (mg) |
|---|---|---|---|---|
| 4A3-SC7 | DC60855 | 1411.07 | 11.9 | 0.167917 |
| DOPE | DC33634 | 744.03 | 11.9 | 0.088540 |
| Cholesterol | DCD-041 | 386.65 | 23.82 | 0.092100 |
| DMG-PEG2000 | DC40169 | 2507 | 2.38 | 0.059667 |
| Lipid 1A7B13 | DC68023 | 1069.66 | 50 | 0.534830 |
Component order: 4A3-SC7/DOPE/cholesterol/DMG-PEG2000/1A7B13 = 11.90:11.90:23.82:2.38:50 mol%. The reported total lipid:mRNA mass ratio is 40:1. This is not 1A7B13:mRNA or N/P. The conversion uses the bromide-salt MW for 1A7B13 and 2507 for DMG-PEG2000.
Read the complete study conditions, biological results, tolerability and figures →