DC Chemicals

DC67515 · Updated 27 October 2026

CICL-207

Product Datasheet

CICL-207 is a constrained ionizable lipid described in US20250127728A1 for targeted lipid-nanoparticle research. The patent evaluates reporter-mRNA delivery, immune-cell delivery and short-term tolerability in animal models. The results apply to the studied complete nanoparticles and their targeting ligands.

CAS No.Not available
Chemical NameCICL-207
SynonymsCICL207, CICL 207
SMILESCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCC)CC(=O)OC[C@@H]1C[C@@H](OC(=O)CC(COC(=O)CCCCCCCC)COC(=O)CCCCCCCC)CN1C(=O)OCCN(C)C
FormulaC56H100N2O14
M.Wt1025.416
Purity>95% by ELSD-HPLC
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication
  1. Karmali PP, Tanis S, Bao Y. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles. US20250127728A1, published April 24, 2025. Example 17; Examples 66 and 69–72; Tables 9 and 13; Figures 2 and 7–12.

Research evidence

Read detailed Formulation & Performance

Specifications are catalog specifications, not batch test results.